Annie Chen-Allen

Annie Chen-Allen

Associate Professor, Diplomate, ACVIM (Neurology)
Office Phone: 509-335-0711



Texas A&M University, Bachelor of Science, 1995-1998
Texas A&M University, Doctor of Veterinary Medicine, 1998-2002
Washington State University, Small Animal Medicine and Surgery Internship, 2002-2003
Washington State University, Neurology and Neurosurgery Residency, 2003-2006
Washington State University, Masters of Veterinary Sciences, 2005-2008

Research Interests

Neuro-oncology – brain and spinal tumors
Novel therapies for brain tumors
Stereotactic brain biopsy and procedures
WSU Pituitary Team for transsphenoidal hypophysectomy
Cerebrospinal fluid biomarkers for neurological diseases

Select Publications
  • Owen, TJ, Chen AV, Frey, S, Martin, LG, Kalebaugh, T. (2018) Transsphenoidal surgery: Assessing accuracy of an image-guided neuronavigation system to approach the pituitary fossa (sella turcica). Veterinary Surgery DOI:1111/vsu.12906. PMID: 29797411 PMCID:
  • Miller MA, Owen TJ, Bruyette DS, Scott-Moncrieff C, Ramos-Vara J, Weng HY, Chen AV, Martin LG, DuSold DM (2018) Immunohistochemical Evaluation of Canine Pituitary Adenomas Obtained by Transsphenoidal Hypophysectomy. Veterinary Pathology DOI:10.1177/0009858187810 PMID: 29925292 PMCID:
  • Miller MA, Bruyette DS, Scott-Moncrieff JCR, Owen TJ, Ramos-VARA JA, Weng HY, Vanderpool AL, Chen AV, Martin LG, DuSold DM, Jahan S (2018) Histologic findings in canine pituitary glands Veterinary Pathology DOI: 10.1177/0300985818766211 PMID: 29665752 PMCID:
  • Owen TJ, Martin, LG, Chen, AV. (2018) Transsphenoidal Surgery for Pituitary Tumors and Other Sellar Masses. Vet Clin North Am Small Anim Pract. 48(1):129-151. doi: 10.1016/j.cvsm.2017.08.006 PMID: 29056398 PMCID:
  • Thomovsky SA, Chen AV, Kiszonas AM, Lutskas LA. (2016) Goniometry and limb girth in miniature dachshunds. J Vet Med 2016:5846052 PMID: 27403455 PMCID: PMC4925976
  • Brune, JE, Chen AV, Kiszonas AM. (2016) Characterization of iatrogenic blood contamination on lactate dehydrogenase and creatine kinase activity in canine cerebrospinal fluid. J Vet Intern Med. PMID: PMCID:
  • Thomovsky SA, Chen AV, Deavila DM, Kiszonas AM. (2015) A pilot study: serum melatonin levels in normal dogs and dogs with seizures. J Vet Intern Med. 29(4):1268 PMID: PMCID:
  • Cohn-Urbach MR, Chen AV, Haldorson GJ, Thomovsky SA. (2015) Perivascular wall tumor in the brain of a dog. Case Reports Vet Med. 2015:1-4. PMID: PMCID:
  • Kawalilak LT, Chen AV, Roberts GR. (2015) Imaging characteristics of disseminated Geosmithia argillacea causing severe diskospondylitis and meningoencephalomyelitis in a dog. Clinical Case Reports. 3(11):901-906. PMID: 26576269 PMCID: PMC4641471
  • Mitchell JW, Thomovsky SA, Chen AV, Layton AW, Haldorson G, Tucker RL, Roberts GR. (2015) Medulloblastoma in a grizzly bear (ursus arctos horribilis). J Zoo Wildl Med. 46(3):624-628. PMID: PMCID:
  • Houle JC, Chen AV, Brenna AC, Mealey KL, Kiszonas AM. (2015) Determination of optimal storage temperature and duration of analysis of total and isoenzyme lactate dehydrogenase activities in canine serum and cerebrospinal fluid. Vet Clin Pathol. 44(2):253-61. PMID: 25964061 PMCID:
  • Barker A, Williams JM, Chen AV, Bagley RS, Jeffery ND. (2015) Magnetic resonance imaging characteristics of primary hematomyelia in 3 dogs. Can Vet J. 56(3):278-84. PMID: 25750449 PMCID: PMC4327142
  • Chen AV, Thomovsky SA, Brune J, Boswell N, Houle JC. (2014) Evaluation of lactate dehydrogenase and creatine kinase activity in cerebrospinal fluid of dogs with neurological diseases. J Vet Intern Med. 28(4):1355. PMID: PMCID:
  • Thomovsky SA, Chen AV, Tucker RL, Roberts GR, Mattoon JS, Kiszonas AM, Morimoto T. (2014) Accuracy of preoperative computed tomography and magnetic resonance imaging as compared to surgical findings in chondrodystrophic dogs with intervertebral disk disease. J Vet Intern Med. 28(4):1355. PMID: PMCID:
  • Krull DP, Thomovsky SA, Chen AV, Mealey KA, Papich MG. (2014) Evaluation of transdermal administration of phenobarbital in healthy cats. J Vet Intern Med. 28(3):1016. PMID: PMCID:
  • Allen AJ, Chen AV, Barrington G, Bagley RB. (2014) Caudal occipital malformation syndrome of a 6 year old female Huacaya Alpaca. J Vet Intern Med. 28(2):693-5. PMID: 24524756 PMCID: PMC4857968
  • Young BD, Fosgate GT, Holmes SP, Wolff CA, Chen-Allen AV, Kent M, Platt SR, Savage MY, Schatzberg SJ, Levine JM. (2014) Evaluation of standard magnetic characteristics used to differentiate neoplastic, inflammatory, and vascular brain lesions in dogs. Vet Radiol Ultrasound. 55(4):399-406. PMID: 24467341 PMCID:
  • Brenna AC, Chen AV, Houle JC, Mealey KM, Thomovsky SA. (2013) Determination of stability and storage parameters for optimal detection of creatine kinase and its isoenzymes in canine serum and cerebrospinal fluid. J Vet Intern Med. 27:678. PMID: PMCID:
  • Houle JC, Chen AV, Brenna AC, Mealey KM, Thomovsky SA. (2013) Activity and distribution of lactate dehydrogenase and its isoenzymes in the serum and cerebrospinal fluid of healthy canines. J Vet Intern Med. 27:678-9. PMID: PMCID:
  • Houle JC, Chen AV, Brenna AC, Mealey KM, Thomovsky SA. (2013) Determination of stability and storage parameters for optimal detection of lactate dehydrogenase and its isoenzymes in canine serum and cerebrospinal fluid. J Vet Intern Med. 27:680-1. PMID: PMCID:
  • Thomovsky S, Chen-Allen AV. (2013) Will he walk again? Only Dr. Nociception knows! Vet J. 198(1):7-8. PMID: PMCID:
  • Van Wie EY, Fosgate GT, Mankin JM, Jeffery ND, Kerwin SC, Levine GJ, Greatting HH, Chen AV, Barker AK, Levine JM. (2013) Prospectively recorded versus medical record-derived spinal cord injury scores in dogs with intervertebral disk herniation. J Vet Intern Med. 27(5):1273-7 PMID: PMCID:
  • Sondgeroth KS, McElwain TF, Allen AJ, Chen AV, Lau AO. (2013) Loss of neurovirulence is associated with reduction of cerebral capillary sequestration during acute babesia bovis infection. Parsit Vectors. 16(1):181. PMID: PMCID:
  • Andersen BM, Pluhar GE, Seiler CE, Goulart MR, Grogan PT, SantaCruz KS, Schutten MM, Meints JP, Gallardo JL, Carlson C, O’Sullivan MG, Bentley RT, Packer RA, Thomovsky SA, Chen AV, Faissler D, Chen W, Hunt MA, Ohlfest JR. (2013) Vaccination for invasive canine meningioma induces in situ production of antibodies capable of antibody-dependent cell-mediated cytotoxicity. Cancer Research. 73(19):2987-97. PMID: PMCID:
  • Chohan, AS, Greene SA, Keegan BD, Grubb TL, Chen AV. (2013) Intracranial pressure and cardiopulmonary variables during isoflurane or sevoflurane anesthesia at various minimum alveolar concentration multiples in normocapnic dogs. Am J Vet Res. 74(3):369-74. PMID: PMCID:
  • Namatame E, Chen AV, Thomovsky S, Tucker RL. (2013) Successful long-term use of itraconanzole for the treatment of Aspergillus diskospondylitis in a dog. Case Reports Vet Med. 2013:1-4. PMID: PMCID:
  • Harris JM, Chen AV, Tucker RL, Mattoon JS. (2013) Signalment, clinical features and magnetic resonance imaging characteristics of 23 cases of diskospondylitis in dogs. J Am Vet Med Assoc. 242(3):359-65. PMID: PMCID:
  • Thomovsky SA, Chen AV, Roberts G. (2012) Spinal cord compression in two related Ursus arctos horribilis. J ZooWildl Med. 43(3):588-95. PMID: PMCID:
  • Wolff CA, Holmes SP, Young BD, Chen AV, Kent M, Platt SR, Savage MY, Schatzberg SJ, Fosgate GT, Levine JM. (2012) Magnetic resonance imaging for the differentiation of neoplastic, inflammatory and cerebrovascular brain disease in dogs. J Vet Intern Med. 26(3):589-97. PMID: PMCID:
  • Martinez SE, Bowen KA, Remsberg DM, Takemoto JK, Wright HM, Chen-Allen AV, Davies NM. (2012) High performance liquid chromatographic analysis of lacosamide in canine serum using ultraviolet detection: application to pre-clinical pharmokinetics in dogs. Biomed Chromatogr. 26(5):606-9. PMID: PMCID:
  • Krugman L, Bryan JN, Mealey KL, Chen AV. (2012) Vincristine-induced central neurotoxicity in a collie homozygous for the ABCB1Δ mutation. J Small Anim Pract. 53(3):185-7. PMID: PMCID:
  • Wright HM, Chen AV, Martinez SE, Davies NM. (2012) Pharmacokinetics of oral rufinamide in dogs. J Vet Pharm Thera. 35(6)529-33. PMID: PMCID:
  • Wright HM, Chen AV, Talcott PA, Poppenga RH, Mealey KL. (2011) Intravenous fat emulsion (IFE) for treatment of ivermectin toxicosis in 3 dogs homozygous for the ABCB1-1Δ gene mutation. J Vet Emerg Crit Care. 21(6):666-72. PMID: PMCID:
  • Chen AV, Wininger FA, Frey S, Comeau R, Bagley RS, Tucker RL, Schneider AR, Gay JM. (2011) Description and validation of a magnetic resonance imaging – guided stereotactic brain biopsy device in the dog. Vet Radiol Ultrasound. 52(5):534-7. PMID: PMCID:
  • Spall B, Chen AV, Tucker RL, Lahmers KK, Righter DJ, Hayles J. (2011) Imaging Diagnosis – Metastatic Adrenal Pheochromocytoma in a Dog. Vet Radiol Ultrasound. 53(5):534-7. PMID: PMCID:
  • Young BD, Levine JM, Porter BF, Chen-Allen AV, Rossmeisl JH, Platt SR, Kent M, Fostgate GT, Schatzberg SG. (2011) Magnetic resonance imaging features of intracranial astrocytomas and oligodendrogliomas in dogs. Vet Radiol Ultrasound. (52):132-141. PMID: PMCID:
  • O’Brien CS, Bagley RS, Hicks DH, Chen AV, Wininger FA, Brumitt JW. (2010) Gamma-irradiated calvarium allograft cranioplasty in a cat following brain tumor removal. J Am Anim Hosp Assoc. 46:268-273. PMID: PMCID:
  • Schneider AR, Chen AV, Tucker RL. (2010) Imaging diagnosis – vertebral canal porcupine quill with presumptive secondary arachnoid diverticulum. Vet Radiol Ultrasound 51(2):152-4. PMID: PMCID:
  • Chen AV, Bagley RS, Talcott PA. (2010) Confirmed 2,4-dichlorophenoxyacetic acid (2,4-D) toxicosis in a dog. J Am Anim Hosp Assoc. 46:43-47. PMID: PMCID:
  • Levine JM, Fostgate GT, Chen AV, Rushing R, Nghiem PP, Platt RS, Bagley RS, Kent M, Hicks DG, Young BD, Schatzberg SJ. (2009) Magnetic resonance imaging in dogs with neurologic impairment due to acute thoracolumbar intervertebral disk herniation. J of Vet Intern. 23(6):1220-1226. PMID: PMCID:
  • Wills TB, Chen AV, Haldorson GJ. (2009) Intracranial mass in a cat. Vet Clin Path. 38(1):39-41. PMID: PMCID:
  • Hicks DG, Pitts MJ, Bagley RS, Vasavada A, Simon J, Chen AV, Wininger FA. (2009) In vitro biomechanical evaluation of a novel internal fixation implant and a traditional pin with polymethylmethacrylate internal fixation implant used to stabilize the C4-5 vertebral motion unit in canine cervical spines. Am J Vet Res. 70(6):719-726. PMID: PMCID:
  • Chen AV, Bagley RS, West CL, Gavin PR, Tucker RL. (2005) Fecal incontinence and spinal cord abnormalities in seven dogs. J Am Vet Med Assoc. 227:1945-1951. PMID: PMCID: